KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.17 | - |
L-o-tyrosine | pH 7.5, 37°C, recombinant enzyme | Aspergillus fumigatus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | activates | Aspergillus fumigatus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
dimethylallyl diphosphate + L-tryptophan | Aspergillus fumigatus | C-7 prenylation | diphosphate + 7-(3-methylbut-2-enyl)-L-tryptophan | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Aspergillus fumigatus | Q4WYG3 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
dimethylallyl diphosphate + L-o-tyrosine | C-5 prenylation, proposed reaction mechanism, overview | Aspergillus fumigatus | diphosphate + 5-(3-methylbut-2-enyl)-L-o-tyrosine | - |
? | |
dimethylallyl diphosphate + L-tryptophan | C-7 prenylation | Aspergillus fumigatus | diphosphate + 7-(3-methylbut-2-enyl)-L-tryptophan | - |
? | |
dimethylallyl diphosphate + L-tyrosine | O-4 prenylation | Aspergillus fumigatus | diphosphate + 5-[(2E)-pent-2-en-1-yl]-L-tryptophan | - |
? | |
additional information | HR-ESI-MS and NMR product analysis. No activity with L-3-tyrosine | Aspergillus fumigatus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
7-DMATS | - |
Aspergillus fumigatus |
tryptophan C7-prenyltransferase | - |
Aspergillus fumigatus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Aspergillus fumigatus |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.045 | - |
L-o-tyrosine | pH 7.5, 37°C, recombinant enzyme | Aspergillus fumigatus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Aspergillus fumigatus |
General Information | Comment | Organism |
---|---|---|
evolution | the enzyme is part of the DMATS superfamily | Aspergillus fumigatus |
metabolism | the enzyme is involved in the biosynthesis of astechrome | Aspergillus fumigatus |
kcat/KM Value [1/mMs-1] | kcat/KM Value Maximum [1/mMs-1] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.265 | - |
L-o-tyrosine | pH 7.5, 37°C, recombinant enzyme | Aspergillus fumigatus |