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Literature summary for 2.5.1.80 extracted from

  • Fan, A.; Winkelblech, J.; Li, S.M.
    Impacts and perspectives of prenyltransferases of the DMATS superfamily for use in biotechnology (2015), Appl. Microbiol. Biotechnol., 99, 7399-7415.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
recombinant enzyme overexpression Aspergillus fumigatus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
dimethylallyl diphosphate + L-tryptophan Aspergillus fumigatus
-
diphosphate + 7-(3-methylbut-2-enyl)-L-tryptophan
-
?

Organism

Organism UniProt Comment Textmining
Aspergillus fumigatus Q4WYG3 gene 7-DMATS
-

Purification (Commentary)

Purification (Comment) Organism
recombinant enzyme Aspergillus fumigatus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-pentenyl diphosphate + L-tryptophan C-5 prenylation Aspergillus fumigatus diphosphate + 5-(pent-2-enyl)-L-tryptophan
-
?
benzyl diphosphate + L-tryptophan C-5 prenylation Aspergillus fumigatus diphosphate + 5-benzyl-L-tryptophan
-
?
dimethylallyl diphosphate + 1-methyl-DL-tryptophan
-
Aspergillus fumigatus diphosphate + 1-methyl-4-(3-methylbut-2-enyl)-DL-tryptophan
-
?
dimethylallyl diphosphate + 11-methyl-DL-tryptophan
-
Aspergillus fumigatus diphosphate + 11-methyl-4-(3-methylbut-2-enyl)-DL-tryptophan
-
?
dimethylallyl diphosphate + 3-iodo-L-tyrosine C-4 prenylation Aspergillus fumigatus diphosphate + 3-iodo-4-(3-methylbut-2-enyl)-L-tyrosine
-
?
dimethylallyl diphosphate + 4-amino-L-phenylalanine C-4 prenylation Aspergillus fumigatus diphosphate + 4-amino-3-(3-methylbut-2-enyl)-L-phenylalanine
-
?
dimethylallyl diphosphate + 4-methyl-DL-tryptophan
-
Aspergillus fumigatus diphosphate + 4-methyl-7-(3-methylbut-2-enyl)-DL-tryptophan
-
?
dimethylallyl diphosphate + 5-bromo-L-tryptophan low activity Aspergillus fumigatus diphosphate + 5-bromo-4-(3-methylbut-2-enyl)-L-tryptophan
-
?
dimethylallyl diphosphate + 5-hydroxy-L-tryptophan
-
Aspergillus fumigatus diphosphate + 5-hydroxy-4-(3-methylbut-2-enyl)-L-tryptophan
-
?
dimethylallyl diphosphate + 5-methyl-DL-tryptophan
-
Aspergillus fumigatus diphosphate + 5-methyl-4-(3-methylbut-2-enyl)-DL-tryptophan
-
?
dimethylallyl diphosphate + 6-fluoro-DL-tryptophan
-
Aspergillus fumigatus diphosphate + 6-fluoro-4-(3-methylbut-2-enyl)-DL-tryptophan
-
?
dimethylallyl diphosphate + 6-methyl-DL-tryptophan low activity Aspergillus fumigatus diphosphate + 6-methyl-4-(3-methylbut-2-enyl)-DL-tryptophan
-
?
dimethylallyl diphosphate + beta-homo-L-tryptophan
-
Aspergillus fumigatus ?
-
?
dimethylallyl diphosphate + D-tryptophan low activity Aspergillus fumigatus diphosphate + 4-(3-methylbut-2-enyl)-D-tryptophan
-
?
dimethylallyl diphosphate + DL-indole-3-lactic acid
-
Aspergillus fumigatus ?
-
?
dimethylallyl diphosphate + indole-3-propionic acid
-
Aspergillus fumigatus ?
-
?
dimethylallyl diphosphate + L-abrine
-
Aspergillus fumigatus ?
-
?
dimethylallyl diphosphate + L-o-tyrosine C-4 prenylation Aspergillus fumigatus diphosphate + 4-(3-methylbut-2-enyl)-L-o-tyrosine 4-dimethylallyl-L-o-tyrosine ?
dimethylallyl diphosphate + L-tryptophan
-
Aspergillus fumigatus diphosphate + 7-(3-methylbut-2-enyl)-L-tryptophan
-
?
dimethylallyl diphosphate + N-acetyl-DL-tryptophan
-
Aspergillus fumigatus diphosphate + N-acetyl-4-(3-methylbut-2-enyl)-DL-tryptophan
-
?
methylallyl diphosphate + L-tryptophan C-4 and C-5 prenylation Aspergillus fumigatus diphosphate + 4-(but-2-enyl)-L-tryptophan
-
?
methylallyl diphosphate + L-tryptophan C-4 and C-5 prenylation Aspergillus fumigatus diphosphate + 5-(but-2-enyl)-L-tryptophan
-
?
additional information no activity with 7-methyl-DL-tryptophan, alpha-methyl-L-tyrosine, L-m-tyrosine, and D-tyrosine. The enzyme is also active with hydroxynaphthalenes which it prenylates at C-4 or C-1, overview Aspergillus fumigatus ?
-
?

Synonyms

Synonyms Comment Organism
7-DMATS
-
Aspergillus fumigatus

General Information

General Information Comment Organism
evolution the enzyme is part of the DMATS superfamily Aspergillus fumigatus