Literature summary for 2.5.1.78 extracted from

Braden, B.C.; Velikovsky, C.A.; Cauerhff, A.A.; Polikarpov, I.; Goldbaum, F.A.
Divergence in macromolecular assembly: X-ray crystallographic structure analysis of lumazine synthase from Brucella abortus (2000), J. Mol. Biol., 297, 1031-1036.

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Crystallization (Commentary)

Crystallization (Comment)	Organism
three-dimensional X-ray crystal structure of the enzyme solved and refined at 2.7 A resolution to a final R-value of 0.18. Structures of the enzyme from Bacillus subtilis and Bruvella abortus are compared	Brucella abortus

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
5-amino-6-(1-D-ribitylamino)pyrimidine-2,4(1H,3H)-dione + (S)-2-hydroxy-3-oxobutyl dihydrogen phosphate	Brucella abortus	-	6,7-dimethyl-8-(1-D-ribityl)lumazine + phosphate + 2 H2O	-	?

Organism

Organism	UniProt	Comment	Textmining
Brucella abortus	P61711	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
5-amino-6-(1-D-ribitylamino)pyrimidine-2,4(1H,3H)-dione + (S)-2-hydroxy-3-oxobutyl dihydrogen phosphate	-	Brucella abortus	6,7-dimethyl-8-(1-D-ribityl)lumazine + phosphate + 2 H2O	-	?

Subunits

Subunits	Comment	Organism
pentamer	-	Brucella abortus

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Release 2023.1 (January 2023)