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Literature summary for 2.5.1.73 extracted from

  • O'Donoghue, P.; Sethi, A.; Woese, C.R.; Luthey-Schulten, Z.A.
    The evolutionary history of Cys-tRNACys formation (2005), Proc. Natl. Acad. Sci. USA, 102, 19003-19008.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
phylogenetic analysis, overview Methanospirillum hungatei
phylogenetic analysis, overview Methanopyrus kandleri
phylogenetic analysis, overview Archaeoglobus fulgidus
phylogenetic analysis, overview Methanococcoides burtonii

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
O-phospho-L-seryl-tRNACys + sulfate Methanospirillum hungatei evolutionary history of Cys-tRNACys formation, overview L-cysteinyl-tRNACys + phosphate
-
?
O-phospho-L-seryl-tRNACys + sulfate Methanopyrus kandleri evolutionary history of Cys-tRNACys formation, overview L-cysteinyl-tRNACys + phosphate
-
?
O-phospho-L-seryl-tRNACys + sulfate Archaeoglobus fulgidus evolutionary history of Cys-tRNACys formation, overview L-cysteinyl-tRNACys + phosphate
-
?
O-phospho-L-seryl-tRNACys + sulfate Methanococcoides burtonii evolutionary history of Cys-tRNACys formation, overview L-cysteinyl-tRNACys + phosphate
-
?

Organism

Organism UniProt Comment Textmining
Archaeoglobus fulgidus O30207 two genes
-
Methanococcoides burtonii Q12W26 two genes
-
Methanopyrus kandleri
-
-
-
Methanospirillum hungatei
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
O-phospho-L-seryl-tRNACys + sulfate
-
Methanospirillum hungatei L-cysteinyl-tRNACys + phosphate
-
?
O-phospho-L-seryl-tRNACys + sulfate
-
Methanopyrus kandleri L-cysteinyl-tRNACys + phosphate
-
?
O-phospho-L-seryl-tRNACys + sulfate
-
Archaeoglobus fulgidus L-cysteinyl-tRNACys + phosphate
-
?
O-phospho-L-seryl-tRNACys + sulfate
-
Methanococcoides burtonii L-cysteinyl-tRNACys + phosphate
-
?
O-phospho-L-seryl-tRNACys + sulfate evolutionary history of Cys-tRNACys formation, overview Methanospirillum hungatei L-cysteinyl-tRNACys + phosphate
-
?
O-phospho-L-seryl-tRNACys + sulfate evolutionary history of Cys-tRNACys formation, overview Methanopyrus kandleri L-cysteinyl-tRNACys + phosphate
-
?
O-phospho-L-seryl-tRNACys + sulfate evolutionary history of Cys-tRNACys formation, overview Archaeoglobus fulgidus L-cysteinyl-tRNACys + phosphate
-
?
O-phospho-L-seryl-tRNACys + sulfate evolutionary history of Cys-tRNACys formation, overview Methanococcoides burtonii L-cysteinyl-tRNACys + phosphate
-
?

Synonyms

Synonyms Comment Organism
SepCysS
-
Methanospirillum hungatei
SepCysS
-
Methanopyrus kandleri
SepCysS
-
Archaeoglobus fulgidus
SepCysS
-
Methanococcoides burtonii

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate dependent on Methanospirillum hungatei
pyridoxal 5'-phosphate dependent on Methanopyrus kandleri
pyridoxal 5'-phosphate dependent on Archaeoglobus fulgidus
pyridoxal 5'-phosphate dependent on Methanococcoides burtonii