Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
36000 | - |
gel filtration, fraction A and B | Homo sapiens |
38000 | - |
1 * 38000, SDS-PAGE, B1 | Homo sapiens |
39500 | - |
1 * 39500, SDS-PAGE, B2 and B3 | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
porphobilinogen | Homo sapiens | - |
? | - |
? | |
porphobilinogen | Bos taurus | - |
? | - |
? | |
porphobilinogen | Cereibacter sphaeroides | - |
? | - |
? | |
porphobilinogen | Spinacia oleracea | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Cereibacter sphaeroides | - |
- |
- |
Homo sapiens | - |
- |
- |
Spinacia oleracea | - |
spinach | - |
Purification (Comment) | Organism |
---|---|
3 isoenzymes | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
callus | tissue | Bos taurus | - |
erythrocyte | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Homo sapiens |
additional information | - |
- |
Cereibacter sphaeroides |
Storage Stability | Organism |
---|---|
purified enzyme loses its activity when it is frozen | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4 porphobilinogen | in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75 | Homo sapiens | uroporphyrinogen III + 4 NH3 | - |
? | |
4 porphobilinogen | in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75 | Bos taurus | uroporphyrinogen III + 4 NH3 | - |
? | |
4 porphobilinogen | in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75 | Cereibacter sphaeroides | uroporphyrinogen III + 4 NH3 | - |
? | |
4 porphobilinogen | in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75 | Spinacia oleracea | uroporphyrinogen III + 4 NH3 | - |
? | |
4 porphobilinogen + H2O | - |
Homo sapiens | hydroxylmethylbilane + 4 NH3 | - |
? | |
4 porphobilinogen + H2O | - |
Bos taurus | hydroxylmethylbilane + 4 NH3 | - |
? | |
4 porphobilinogen + H2O | - |
Cereibacter sphaeroides | hydroxylmethylbilane + 4 NH3 | - |
? | |
4 porphobilinogen + H2O | - |
Spinacia oleracea | hydroxylmethylbilane + 4 NH3 | - |
? | |
porphobilinogen | - |
Homo sapiens | ? | - |
? | |
porphobilinogen | - |
Bos taurus | ? | - |
? | |
porphobilinogen | - |
Cereibacter sphaeroides | ? | - |
? | |
porphobilinogen | - |
Spinacia oleracea | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | - |
Cereibacter sphaeroides |
monomer | 1 * 38000, SDS-PAGE, B1 | Homo sapiens |
monomer | 1 * 39500, SDS-PAGE, B2 and B3 | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
porphobilinogen deaminase | - |
Homo sapiens |
porphobilinogen deaminase | - |
Cereibacter sphaeroides |
UPGI-S | - |
Homo sapiens |
uroporphyrinogen I synthase | - |
Homo sapiens |