Literature summary for 2.5.1.60 extracted from

Joachimiak, L.; Marchwicka, A.; Gendaszewska-Darmach, E.; Blazewska, K.M.
Synthesis and biological evaluation of imidazole-bearing alpha-phosphonocarboxylates as inhibitors of Rab geranylgeranyl transferase (RGGT) (2018), ChemMedChem, 13, 842-851 .

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Inhibitors

Inhibitors	Comment	Organism	Structure
2-fluoro-3-(1-methyl-1H-imidazol-5-yl)-2-phosphonopropanoic acid	compound inhibits isoform Rab11A, but not Rap1A/Rap1B prenylation in HeLa cells	Homo sapiens
2-fluoro-3-(1H-imidazol-4(5)-yl)-2-phosphonopropanoic acid	compound inhibits isoform Rab11A, but not Rap1A/Rap1B prenylation in HeLa cells	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P24386	-	-

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Release 2023.1 (January 2023)