Literature summary for 2.5.1.60 extracted from

Kalinin, A.; Thom�, N.H.; Iakovenko, A.; Heinemann, I.; Rostkova, E.; Constantinescu, A.T.; Alexandrov, K.
Expression of mammalian geranylgeranyltransferase type-II in Escherichia coli and its application for in vitro prenylation of Rab proteins (2001), Protein Expr. Purif., 22, 84-91.

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Cloned(Commentary)

Cloned (Comment)	Organism
development of a two plasmid expression system in Escherichia coli that achieves large quantities of enzyme	Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
100000	-	-	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
recombinant enzyme	Rattus norvegicus

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
0.098	-	-	Rattus norvegicus

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
geranylgeranyl diphosphate + protein-cysteine	enzyme catalyses the transfer of two 20-carbon geranylgeranyl groups from geranylgeranyl diphosphate onto C-terminal cysteine residues of Rab-proteins	Rattus norvegicus	S-geranylgeranyl-protein + diphosphate	-	?

Subunits

Subunits	Comment	Organism
heterodimer	-	Rattus norvegicus

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Release 2023.1 (January 2023)