Literature summary for 2.5.1.58 extracted from

Hosokawa, A.; Wollack, J.W.; Zhang, Z.; Chen, L.; Barany, G.; Distefano, M.D.
Evaluation of an alkyne-containing analogue of farnesyl diphosphate as a dual substrate for protein-prenyltransferases (2007), Int. J. Pept. Res. Ther., 13, 345-354.

No PubMed abstract available

Search for more literature for 2.5.1.58

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli BL21(DE3)/pRD57 cells	Saccharomyces cerevisiae

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Mg2+	required for activity	Saccharomyces cerevisiae
Zn2+	required for activity	Saccharomyces cerevisiae

Organism

Organism	UniProt	Comment	Textmining
Saccharomyces cerevisiae	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Saccharomyces cerevisiae

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
0.867	-	recombinant enzyme, at 30°C	Saccharomyces cerevisiae

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
12-propargoxyfarnesyl diphosphate + N-dansyl-Gly-Cys-Val-Ile-Ala-OH	-	Saccharomyces cerevisiae	diphosphate + propargoxyfarnesyl N-dansyl-Gly-Cys-Val-Ile-Ala-OH	-	?

Synonyms

Synonyms	Comment	Organism
PFTase	-	Saccharomyces cerevisiae
protein-farnesyltransferase	-	Saccharomyces cerevisiae

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Release 2023.1 (January 2023)