Literature summary for 2.5.1.58 extracted from

Guida, W.C.; Hamilton, A.D.; Crotty, J.W.; Sebti, S.M.
Protein farnesyltransferase: flexible docking studies on inhibitors using computational modeling (2006), J. Comput. Aided Mol. Des., 19, 871-885.

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Inhibitors

Inhibitors	Comment	Organism	Structure
CVFM	-	Rattus norvegicus
CVIM	-	Rattus norvegicus
DPI-1	-	Rattus norvegicus
FTI-2148	-	Rattus norvegicus
FTI-276	-	Rattus norvegicus
L-739,750	-	Rattus norvegicus
R-115777	-	Rattus norvegicus

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Zn2+	FTase is a zinc metalloenzyme with a Zn2+ ion ligated to a histidine, cysteine and aspartate	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Synonyms

Synonyms	Comment	Organism
FTase	-	Rattus norvegicus

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Release 2023.1 (January 2023)