Any feedback?
Literature summary for 2.5.1.56 extracted from
- Design, synthesis, and structural elucidation of novel NmeNANAS inhibitors for the treatment of meningococcal infection (2019), PLoS ONE, 14, e0223413 .
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 5-(carboxyamino)-3,5-dideoxy-2-O-phosphono-D-erythro-L-manno-nononic acid | residues Glu25, Gln55, Asn74, Thr110, Phe112, Lys129, Asn184, Tyr186, Ser213, His215, Glu234, Phe288, and Arg314 amino acids are in close proximity and have essential interactions with the ligand | Neisseria meningitidis |  |
| ethyl 3-benzoyl-2,7-dimethyl indolizine-1-carboxylate | inhibitor identified by molecular modeling. The compound shows important polar interactions with the Mn2+ ion, as well as with the Gln55, Asn184, and Arg314 residues | Neisseria meningitidis | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Neisseria meningitidis | - |
- |
- |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
