Literature summary for 2.5.1.54 extracted from

Balachandran, N.; To, F.; Berti, P.J.
Linear free energy relationship analysis of transition state mimicry by 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) oxime, a DAHP synthase inhibitor and phosphate mimic (2017), Biochemistry, 56, 592-601 .

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Inhibitors

Inhibitors	Comment	Organism	Structure
3-deoxy-D-arabinoheptulosonate-7-phosphate oxime	inhibitor shows a good correlation between transition state stabilization and inhibition. DAHP oxime is mimicking the first irreversible transition state of the DAHP synthase reaction, presumably phosphate departure from the tetrahedral intermediate	Escherichia coli

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	C3TIE2	isoform DAHPS(Phe)	-

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Release 2023.1 (January 2023)