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Literature summary for 2.5.1.47 extracted from

  • Wang, C.; Zheng, L.; Tang, Z.; Sun, S.; Ma, J.F.; Huang, X.Y.; Zhao, F.J.
    OASTL-A1 functions as a cytosolic cysteine synthase and affects arsenic tolerance in rice (2020), J. Exp. Bot., 71, 3678-3689 .
    View publication on PubMed
Search for more literature for 2.5.1.47

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3
-
 hydrogen sulfide pH 7.5, 25°C Oryza sativa Japonica Group
3.8
-
 O-acetyl-L-Ser pH 7.5, 25°C Oryza sativa Japonica Group

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Oryza sativa Japonica Group 5829
-

Organism

Organism UniProt Comment Textmining
Oryza sativa Japonica Group Q9XEA8
-
-

Source Tissue

Source Tissue Comment Organism Textmining
node expressed at the reproductive stage Oryza sativa Japonica Group
-
root expressed in roots at the vegetative growth stage, expressed in the outer cortex and the vascular cylinder in the root mature zone Oryza sativa Japonica Group
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
O-acetyl-L-Ser + hydrogen sulfide
-
 Oryza sativa Japonica Group L-Cys + acetate
-
 ?

Subunits

Subunits Comment Organism
? x * 35100, SDS-PAGE, recombinant protein Oryza sativa Japonica Group

Synonyms

Synonyms Comment Organism
OASTL-A1
-
 Oryza sativa Japonica Group
Os03g53650
-
 Oryza sativa Japonica Group
RCS3
-
 Oryza sativa Japonica Group

Expression

Organism Comment Expression
Oryza sativa Japonica Group expression in roots is strongly induced by As exposure up

General Information

General Information Comment Organism
physiological function knockout of OASTL-A1 leads to significantly lower levels of cysteine, glutathione, and phytochelatins in roots and increased sensitivity to arsenate stress. The knockout reduces As accumulation in the roots, but increases As accumulation in shoots. OASTL-A1 is able to complement an Escherichia coli cysteine synthase-deficient mutant Oryza sativa Japonica Group