Literature summary for 2.5.1.46 extracted from

Burnat, M.; Li, B.; Kim, S.; Michael, A.; Flores, E.
Homospermidine biosynthesis in the cyanobacterium Anabaena requires a deoxyhypusine synthase homologue and is essential for normal diazotrophic growth (2018), Mol. Microbiol., 109, 763-780 .

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
[eIF5A-precursor]-lysine + spermidine	Nostoc sp. PCC 7120 = FACHB-418	the enzyme is involved in synthesis of synthesis of homospermidine	[eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine	-	?

Organism

Organism	UniProt	Comment	Textmining
Nostoc sp. PCC 7120 = FACHB-418	Q8YQL7	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
heterocyst	SpeY accumulates in vegetative cells but also at significant levels in heterocysts	Nostoc sp. PCC 7120 = FACHB-418	-
vegetative cell	SpeY accumulates in vegetative cells but also at significant levels in heterocysts	Nostoc sp. PCC 7120 = FACHB-418	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
[eIF5A-precursor]-lysine + spermidine	overall reaction	Nostoc sp. PCC 7120 = FACHB-418	[eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine	-	?
[eIF5A-precursor]-lysine + spermidine	the enzyme is involved in synthesis of synthesis of homospermidine	Nostoc sp. PCC 7120 = FACHB-418	[eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine	-	?

Synonyms

Synonyms	Comment	Organism
speY	-	Nostoc sp. PCC 7120 = FACHB-418

General Information

General Information	Comment	Organism
metabolism	the enzyme is involved in synthesis of synthesis homospermidine	Nostoc sp. PCC 7120 = FACHB-418

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Release 2023.1 (January 2023)