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Literature summary for 2.5.1.43 extracted from

  • Aung, M.S.; Masuda, H.; Nozoye, T.; Kobayashi, T.; Jeon, J.S.; An, G.; Nishizawa, N.K.
    Nicotianamine synthesis by OsNAS3 is important for mitigating iron excess stress in rice (2019), Front. Plant Sci., 10, 660 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.5.1.43

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3 S-adenosyl-L-methionine Oryza sativa rice synthesizes nicotianamine with OsNAS3 under Fe excess in roots and shoots. Nicotianamine and deoxymugineic acid synthesized by OsNAS3 under excess Fe conditions contribute to Fe detoxification in rice 3 S-methyl-5'-thioadenosine + nicotianamine
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 ?

Organism

Organism UniProt Comment Textmining
Oryza sativa Q0D3F2
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Source Tissue

Source Tissue Comment Organism Textmining
epidermis OsNAS3 is widely expressed in roots, especially in vascular bundle, epidermis, exodermis, stem, and old leaf tissues under Fe excess compared to control plants Oryza sativa
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exodermis OsNAS3 is widely expressed in roots, especially in vascular bundle, epidermis, exodermis, stem, and old leaf tissues under Fe excess compared to control plants Oryza sativa
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leaf OsNAS3 is widely expressed in roots, especially in vascular bundle, epidermis, exodermis, stem, and old leaf tissues under Fe excess compared to control plants Oryza sativa
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root OsNAS3 is widely expressed in roots, especially in vascular bundle, epidermis, exodermis, stem, and old leaf tissues under Fe excess compared to control plants Oryza sativa
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stem OsNAS3 is widely expressed in roots, especially in vascular bundle, epidermis, exodermis, stem, and old leaf tissues under Fe excess compared to control plants Oryza sativa
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vascular bundle OsNAS3 is widely expressed in roots, especially in vascular bundle, epidermis, exodermis, stem, and old leaf tissues under Fe excess compared to control plants Oryza sativa
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3 S-adenosyl-L-methionine
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 Oryza sativa 3 S-methyl-5'-thioadenosine + nicotianamine
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 ?
3 S-adenosyl-L-methionine rice synthesizes nicotianamine with OsNAS3 under Fe excess in roots and shoots. Nicotianamine and deoxymugineic acid synthesized by OsNAS3 under excess Fe conditions contribute to Fe detoxification in rice Oryza sativa 3 S-methyl-5'-thioadenosine + nicotianamine
-
 ?

Synonyms

Synonyms Comment Organism
OsNAS3
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 Oryza sativa

Expression

Organism Comment Expression
Oryza sativa strongly induced with excess Fe in most rice tissues, particularly old leaves, suggesting that it may play a vital role under excess Fe conditions up

General Information

General Information Comment Organism
malfunction OsNAS3 knockout plants are sensitive to excess Fe, exhibiting inferior growth, reduced dry weight, severer leaf bronzing, and greater Fe accumulation in their leaves than non-transformants with excess Fe Oryza sativa
metabolism rice synthesizes nicotianamine with OsNAS3 under Fe excess in roots and shoots. Nicotianamine and deoxymugineic acid synthesized by OsNAS3 under excess Fe conditions contribute to Fe detoxification in rice Oryza sativa