Inhibitors | Comment | Organism | Structure |
---|---|---|---|
spirohexaline | - |
Penicillium brasilianum | |
viridicatumtoxin | - |
Penicillium brasilianum |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Penicillium brasilianum | - |
- |
- |
Penicillium brasilianum FKI-3368 | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
undecaprenyl pyrophosphate synthase | - |
Penicillium brasilianum |
UPP synthase | - |
Penicillium brasilianum |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.004 | - |
pH and temperature not specified in the publication | Penicillium brasilianum | viridicatumtoxin | |
0.009 | - |
pH and temperature not specified in the publication | Penicillium brasilianum | spirohexaline |
General Information | Comment | Organism |
---|---|---|
physiological function | undecaprenyl diphosphate is a key lipid involved in the biosynthesis of peptidoglycan and other cell wall polysaccharide components, such as lipopolysaccharides, enterobacterial common antigen, capsule polysaccharides and teichoic acids. In the cell wall synthetic pathway, UPP is needed for the synthesis and transport of hydrophilic GlcNAc-MurNAc-pentapeptides across the hydrophobic environment of the cytoplasmic membrane to the externally located sites of polymerization | Penicillium brasilianum |