Activating Compound | Comment | Organism | Structure |
---|---|---|---|
NH4+ | 50 mM, enhances activity approx. 13fold | Methanothermobacter thermautotrophicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
diphosphate | - |
Methanothermobacter thermautotrophicus | |
geranylgeranyl diphosphate | - |
Methanothermobacter thermautotrophicus | |
Li+ | 400 mM, 72% inhibition, slight activation at 50 mM | Methanothermobacter thermautotrophicus | |
additional information | monovalent cations at low concentrations, i.e. 50 mM, enhance activity, at high concentrations, i.e. 400 mM, they are inhibitory, except for K+ | Methanothermobacter thermautotrophicus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
KCl | 200-2300 mM, enhances activity approx. 10fold | Methanothermobacter thermautotrophicus | |
additional information | monovalent cations at low concentrations, i.e. 50 mM, enhance activity, at high concentrations, i.e. 400 mM, they are inhibitory, except for K+ | Methanothermobacter thermautotrophicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
(E,E)-farnesyl diphosphate + isopentenyl diphosphate | Methanothermobacter thermautotrophicus | - |
geranylgeranyl diphosphate + diphosphate | - |
? | |
(E,E)-farnesyl diphosphate + isopentenyl diphosphate | Methanothermobacter thermautotrophicus SF-4 | - |
geranylgeranyl diphosphate + diphosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Methanothermobacter thermautotrophicus | - |
SF-4 | - |
Methanothermobacter thermautotrophicus SF-4 | - |
SF-4 | - |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
(2E,6E)-farnesyl diphosphate + isopentenyl diphosphate = diphosphate + geranylgeranyl diphosphate | ordered-sequential bi bi mechanism | Methanothermobacter thermautotrophicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(E,E)-farnesyl diphosphate + isopentenyl diphosphate | - |
Methanothermobacter thermautotrophicus | geranylgeranyl diphosphate + diphosphate | - |
? | |
(E,E)-farnesyl diphosphate + isopentenyl diphosphate | - |
Methanothermobacter thermautotrophicus SF-4 | geranylgeranyl diphosphate + diphosphate | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
60 | - |
assay at | Methanothermobacter thermautotrophicus |