Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | O00116 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
thyroid cancer cell | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
AGPS | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | downregulation of alkylglycerone phosphate synthase and circRNAs expression has a significant effect on the regulation of biological functions, including cell adhesion, cell cycle and metabolism in various tumor types | down |
General Information | Comment | Organism |
---|---|---|
malfunction | effects of AGPS silencing and knockout on circRNA expression in the thyroid cancer cell line FRO are investigated using circRNAs microarray | Homo sapiens |
metabolism | positive correlation between the expression of alkylglycerone phosphate synthase (AGPS) and the malignant phenotype of thyroid cancer cell lines is identified. The inactivation of AGPS is able to decrease the malignancy of cancer, and inhibits tumor growth and invasion. AGPS is able to regulate the expression of circular RNAs (circRNAs), which may be the mechanism of its anticancer activity | Homo sapiens |