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Literature summary for 2.5.1.26 extracted from

  • Hou, S.; Tan, J.; Yang, B.; He, L.; Zhu, Y.
    Effect of alkylglycerone phosphate synthase on the expression profile of circRNAs in the human thyroid cancer cell line FRO (2018), Oncol. Lett., 15, 7889-7899 .
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Homo sapiens O00116
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-

Source Tissue

Source Tissue Comment Organism Textmining
thyroid cancer cell
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Homo sapiens
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Synonyms

Synonyms Comment Organism
AGPS
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Homo sapiens

Expression

Organism Comment Expression
Homo sapiens downregulation of alkylglycerone phosphate synthase and circRNAs expression has a significant effect on the regulation of biological functions, including cell adhesion, cell cycle and metabolism in various tumor types down

General Information

General Information Comment Organism
malfunction effects of AGPS silencing and knockout on circRNA expression in the thyroid cancer cell line FRO are investigated using circRNAs microarray Homo sapiens
metabolism positive correlation between the expression of alkylglycerone phosphate synthase (AGPS) and the malignant phenotype of thyroid cancer cell lines is identified. The inactivation of AGPS is able to decrease the malignancy of cancer, and inhibits tumor growth and invasion. AGPS is able to regulate the expression of circular RNAs (circRNAs), which may be the mechanism of its anticancer activity Homo sapiens