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Literature summary for 2.5.1.26 extracted from

  • Yang, B.; Li, X.; He, L.; Zhu, Y.
    Computer-aided design of temozolomide derivatives based on alkylglycerone phosphate synthase structure with isothiocyanate and their pharmacokinetic/toxicity prediction and anti-tumor activity in vitro (2018), Biomed. Rep., 8, 235-240 .
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
pharmacology the enzyme reduces ether lipid levels in tumor cells and thus decreases cancer pathogenicity. It is considered to be a target of antitumor drugs, with specific inhibitors expected to have marked advantages over traditional chemotherapy methods Dictyostelium discoideum

Organism

Organism UniProt Comment Textmining
Dictyostelium discoideum O96759
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-

Synonyms

Synonyms Comment Organism
AGPS
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Dictyostelium discoideum
alkylglycerone phosphate synthase
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Dictyostelium discoideum