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Literature summary for 2.5.1.22 extracted from
- Long-range effect of a single mutation in spermine synthase (2018), J. Theor. Comput. Chem., 17, 16135-16146 .
No PubMed abstract available
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| G191S | the mutation at a site far away from the active pocket affects the active site dynamics and thus the functionality of SpmSyn. This suggests that SpmSyn functionality is regulated by networks of interacting residues and thus expands the functional and structural importance beyond the amino acids directly involved in the catalysis | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | P52788 | - |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| SpmSyn | - |
Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| metabolism | the enzyme is critical for maintaining the balance of spermine/spermidine in the cell | Homo sapiens |
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Release 2023.1 (January 2023)
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