Cloned (Comment) | Organism |
---|---|
Escherichia coli codon-optimized gene tsqs, recombinant expression of wild-type and endgineered enzymes in Escherichia coli strain XL1-Blue, coexpression with gene crtN encoding DSQ desaturase from Staphylococcus aureus in Escherichia coli results in carotinoid production and accumulation of C30 carotenoid pigments, which does not happen with coexpression of gene crtI encoding Pantoea ananatis phytoene desaturase, carotenoid pigment analysis, overview | Thermosynechococcus vestitus |
gene hsqs, recombinant expression of a truncated Q33R/D34N/S38N mutant lacking 30 N-terminal residues and 47 C-terminal residues in Escherichia coli strain XL1-Blue, coexpression with gene crtN encoding DSQ desaturase from Staphylococcus aureus in Escherichia coli results in carotinoid production and accumulation of C30 carotenoid pigments, which does not happen with coexpression of gene crtI encoding Pantoea ananatis phytoene desaturase, carotenoid pigment analysis, overview | Homo sapiens |
gene ysqs, recombinant expression of wild-type and endgineered enzymes in Escherichia coli strain XL1-Blue, coexpression with gene crtN encoding DSQ desaturase from Staphylococcus aureus in Escherichia coli results in carotinoid production and accumulation of C30 carotenoid pigments, which does not happen with coexpression of gene crtI encoding Pantoea ananatis phytoene desaturase, carotenoid pigment analysis, overview | Saccharomyces cerevisiae |
Protein Variants | Comment | Organism |
---|---|---|
additional information | construction of a mutant containing three synonymous mutations G1125A, T1128C, T1176C and one nonsynonymous mutation G856A, which corresponds to Gly286Ser exchange, by gene replacement. Various mutations clustered around the residues that are important for NADPH binding effectively convert SQS into a dehydrosqualene synthase, overview | Saccharomyces cerevisiae |
additional information | various mutations clustered around the residues that are important for NADPH binding effectively convert SQS into a dehydrosqualene synthase, overview | Thermosynechococcus vestitus |
additional information | various mutations clustered around the residues that are important for NADPH binding effectively convert SQS into a dehydrosqualene synthase, overview | Homo sapiens |
Q33R/D34N/S38N | the mutations do not affect the enzyme activity | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P37268 | gene hsqs | - |
Saccharomyces cerevisiae | P53866 | gene ysqs | - |
Thermosynechococcus vestitus | - |
gene tsqs | - |
Synonyms | Comment | Organism |
---|---|---|
Erg9 | - |
Saccharomyces cerevisiae |
SQS | - |
Thermosynechococcus vestitus |
SQS | - |
Homo sapiens |
SQS | - |
Saccharomyces cerevisiae |
General Information | Comment | Organism |
---|---|---|
metabolism | squalene synthase catalyzes the first step of sterol/hopanoid biosynthesis in the organism | Thermosynechococcus vestitus |
metabolism | squalene synthase catalyzes the first step of sterol/hopanoid biosynthesis in the organism | Homo sapiens |
metabolism | squalene synthase catalyzes the first step of sterol/hopanoid biosynthesis in the organism | Saccharomyces cerevisiae |