Literature summary for 2.5.1.21 extracted from

Sun, Y.; Zhao, Y.; Wang, L.; Lou, H.X.; Cheng, A.X.
Cloning and expression analysis of squalene synthase, a key enzyme involved in antifungal steroidal glycoalkaloids biosynthesis from Solanum nigrum (2012), Drug Discov. Ther., 6, 242-248.

Search for more literature for 2.5.1.21

Cloned(Commentary)

Cloned (Comment)	Organism
DNA and amino acid sequence determination and analysis, real-time RT-PCR expression analysis	Solanum nigrum

Organism

Organism	UniProt	Comment	Textmining
Solanum nigrum	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
additional information	tissue real-time RTPCR expression analysis, the enzyme is expressed constitutively in all tested tissues, with the highest expression in stems	Solanum nigrum	-
stem	-	Solanum nigrum	-

Expression

Organism	Comment	Expression
Solanum nigrum	infectionn of the plants with Fusarium oxysporum induces the squalene synthase expression	up

General Information

General Information	Comment	Organism
metabolism	squalene synthase is a key enzyme involved in antifungal steroidal glycoalkaloids biosynthesis. Steroidal glycoalkaloids are a family of nitrogenous secondary metabolites acting as phytoalexins, e.g. gamma-solamargine and its aglycone solasodine from Solanum nigrum inhibiting hyphae formation of Fusarium oxysporum	Solanum nigrum

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Release 2023.1 (January 2023)