Activating Compound | Comment | Organism | Structure |
---|---|---|---|
iodoacetic acid | - |
Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | pseudo-first order kinetic constants, simplified Michaelis-Menten steady-state model for simulation of the overall dependence of the rate of product formationon either substrate or enzyme concentrations, with substrate 1-chloro-2,4-dinitrobenzene | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Rattus norvegicus | glutathione transferases from rat liver are able to conjugate GSH to many hydrophobic toxic compounds. Small and hydrophilic disulfides like cystine, cystamine and dithioethanol, and hydrophilic alkylating compounds like iodoacetate, are no substrates of this enzyme. Omega class GST and a peculiar lens GST display a moderate thiol transferase activity with dithioethanol | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
hepatocyte | - |
Rattus norvegicus | - |
lens | - |
Rattus norvegicus | - |
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-chloro-2,4-dinitrobenzene + glutathione | - |
Rattus norvegicus | S-(2,4-dinitrophenyl)glutathione + HCl | - |
? | |
additional information | glutathione transferases from rat liver are able to conjugate GSH to many hydrophobic toxic compounds. Small and hydrophilic disulfides like cystine, cystamine and dithioethanol, and hydrophilic alkylating compounds like iodoacetate, are no substrates of this enzyme. Omega class GST and a peculiar lens GST display a moderate thiol transferase activity with dithioethanol | Rattus norvegicus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
alpha GST | - |
Rattus norvegicus |
GST | - |
Rattus norvegicus |
Mu GST | - |
Rattus norvegicus |
Omega class GST | - |
Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6 | 7.1 | assay at | Rattus norvegicus |