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Literature summary for 2.5.1.18 extracted from

  • Adewale, I.O.; Afolayan, A.
    Organ distribution and kinetics of glutathione transferase from African river prawn, Macrobrachium vollenhovenii (Herklots) (2005), Aquat. Toxicol., 71, 193-202.
    View publication on PubMed
Search for more literature for 2.5.1.18

Inhibitors

Inhibitors Comment Organism Structure
Cl- inhibits reaction with 1-chloro-2,4-dinitrobenzene with IC50: 0.12 mM. No inhibitory effect on the reaction with 7-chloro-4-nitrobenzo-2-oxa-1,3-diazole Macrobrachium vollenhovenii
NaCl IC50: 0.115 mM Macrobrachium vollenhovenii
nitrite
-
 Macrobrachium vollenhovenii

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.03
-
 1-chloro-2,4-dinitrobenzene
-
 Macrobrachium vollenhovenii
2.2
-
 7-Chloro-4-nitrobenzo-2-oxa-1,3-diazole
-
 Macrobrachium vollenhovenii

Organism

Organism UniProt Comment Textmining
Macrobrachium vollenhovenii
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
eye 25 nM/min*mg in crude extract Macrobrachium vollenhovenii
-
hepatopancreas 520 nM/min*mg in crude extract Macrobrachium vollenhovenii
-
intestine 30.5 nM/min*mg in crude extract Macrobrachium vollenhovenii
-
muscle 11 nM/min*mg in crude extract Macrobrachium vollenhovenii
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-chloro-2,4-dinitrobenzene + GSH
-
 Macrobrachium vollenhovenii 1-glutathionyl-2,4-dinitrobenzene + HCl
-
 ?
7-chloro-4-nitrobenzo-2-oxa-1,3-diazole + GSH
-
 Macrobrachium vollenhovenii 7-chloro-4-glutathionylbenzo-2-oxa-1,3-diazole
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
40
-
-
 Macrobrachium vollenhovenii

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
additional information
-
 additional information
-
 Macrobrachium vollenhovenii

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
10
-
 nitrite reaction with 7-chloro-4-nitrobenzo-2-oxa-1,3-diazole Macrobrachium vollenhovenii
17
-
 nitrite reaction with 1-chloro-2,4-dinitrobenzene Macrobrachium vollenhovenii

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.115
-
 IC50: 0.115 mM Macrobrachium vollenhovenii NaCl
0.12
-
 inhibits reaction with 1-chloro-2,4-dinitrobenzene with IC50: 0.12 mM. No inhibitory effect on the reaction with 7-chloro-4-nitrobenzo-2-oxa-1,3-diazole Macrobrachium vollenhovenii Cl-