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Literature summary for 2.5.1.18 extracted from

  • Clark, A.G.; Drake, B.
    Purification and properties of glutathione S-transferases from larvae of Wiseana cervinata (1984), Biochem. J., 217, 41-50.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.5.1.18

Inhibitors

Inhibitors Comment Organism Structure
NaCl 0.2 M, 50% inhibition Wiseana cervinata
S-(2,4-dinitrophenyl)glutathione
-
 Wiseana cervinata

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
22800
-
 2 * 22800 or 2 * 24600, SDS-PAGE Wiseana cervinata
24600
-
 2 * 22800 or 2 * 24600, SDS-PAGE Wiseana cervinata
45000 50000
-
 Wiseana cervinata

Organism

Organism UniProt Comment Textmining
Wiseana cervinata
-
 porina moth
-

Purification (Commentary)

Purification (Comment) Organism
-
 Wiseana cervinata

Reaction

Reaction Comment Organism Reaction ID
RX + glutathione = HX + R-S-glutathione random steady state mechanism Wiseana cervinata
a

Source Tissue

Source Tissue Comment Organism Textmining
larva
-
 Wiseana cervinata
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
108
-
-
 Wiseana cervinata

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
glutathione + 1,2-dichloro-4-nitrobenzene
-
 Wiseana cervinata ?
-
 ?
glutathione + 1-chloro-2,4-dinitrobenzene
-
 Wiseana cervinata S-2,4-dinitrophenylglutathione + HCl
-
 ?
glutathione + 4-nitrobenzyl chloride
-
 Wiseana cervinata ?
-
 ?
glutathione + ethacrynic acid
-
 Wiseana cervinata ?
-
 ?
glutathione + indomethane
-
 Wiseana cervinata ?
-
 ?
glutathione + iodomethane
-
 Wiseana cervinata ?
-
 ?
additional information specificity Wiseana cervinata ?
-
 ?
additional information no substrate: bromosulfophthalein Wiseana cervinata ?
-
 ?
additional information no substrate: 4-nitrobenzyl chloride Wiseana cervinata ?
-
 ?
additional information no substrate: 4-nitropyridine N-oxide Wiseana cervinata ?
-
 ?
additional information no substrate: 1,2-epoxy-3-(4-nitrophenoxy)propane Wiseana cervinata ?
-
 ?
RX + glutathione RX: R: aliphatic, aromatic or heterocyclic, X: sulfate, nitrite or halide, enzyme also catalyzes: the addition of aliphatic epoxides and arene oxides to glutathione, the reduction of polyol nitrate by glutathione to polyol and nitrite, certain isomerization reactions and disulfide interchange Wiseana cervinata HX + R-S-glutathione
-
 ?

Subunits

Subunits Comment Organism
dimer 2 * 22800 or 2 * 24600, SDS-PAGE Wiseana cervinata

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5 8.5
-
 Wiseana cervinata