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Literature summary for 2.5.1.16 extracted from

  • Hewezi, T.; Howe, P.J.; Maier, T.R.; Hussey, R.S.; Mitchum, M.G.; Davis, E.L.; Baum, T.J.
    Arabidopsis spermidine synthase is targeted by an effector protein of the cyst nematode Heterodera schachtii (2010), Plant Physiol., 152, 968-984.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Arabidopsis thaliana using yeast two-hybrid assays, spermidine synthase2 is identified as a specific 10A06 interactor. 10A06 is a cyst nematode (Heterodera glycines) secretory protein able to infect Arabidopsis thaliana, that is secreted as an effector into the developing syncytia during early plant parasitism ?
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Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information using yeast two-hybrid assays, spermidine synthase2 is identified as a specific 10A06 interactor. 10A06 is a cyst nematode (Heterodera glycines) secretory protein able to infect Arabidopsis thaliana, that is secreted as an effector into the developing syncytia during early plant parasitism Arabidopsis thaliana ?
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Synonyms

Synonyms Comment Organism
SPDS2
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Arabidopsis thaliana
spermidine synthase
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Arabidopsis thaliana

General Information

General Information Comment Organism
physiological function transgenic plants expressing the cyst nematode (Heterodera glycines) effector protein 10A06 exhibit elevated SPDS2 mRNA abundance, significantly higher spermidine content, and increased polyamine oxidase activity. The SPDS2 promoter is strongly activated in the nematode-induced syncytia, and transgenic plants overexpressing SPDS2 show enhanced plant susceptibility to Heterodera schachtii. These data lend strong support to a model in which the cyst nematode effector 10A06 exerts its function through the interaction with SPDS2, thereby increasing spermidine content and subsequently polyamine oxidase activity Arabidopsis thaliana