Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Cyclohexylamine | in vitro, 50% inhibition at 0.015 mM, competitive with 1,4-diaminobutane | Trypanosoma brucei brucei | |
S-Adenosyl-1,8-diamino-3-thiooctane | potent, 50% inhibition at 0.025 mM | Trypanosoma brucei brucei |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
74000 | - |
gel filtration and sucrose density gradient centrifugation | Trypanosoma brucei brucei |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-3-methylthio-1-propylamine + 1,4-diaminobutane | Trypanosoma brucei brucei | - |
5'-methylthioadenosine + spermidine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Trypanosoma brucei brucei | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-(5')-3-methylthio-1-propylamine + 1,4-diaminobutane | - |
Trypanosoma brucei brucei | 5'-methylthioadenosine + spermidine | - |
? | |
S-adenosyl-3-methylthio-1-propylamine + 1,4-diaminobutane | - |
Trypanosoma brucei brucei | 5'-methylthioadenosine + spermidine | - |
? |