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Literature summary for 2.5.1.117 extracted from
- Characterization of homogentisate prenyltransferases involved in plastoquinone-9 and tocochromanol biosynthesis (2006), FEBS Lett., 580, 5357-5362.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in Escherichia coli | Chlamydomonas reinhardtii |
| expression in Escherichia coli | Arabidopsis thaliana |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | required | Chlamydomonas reinhardtii |  |
| Mg2+ | required | Arabidopsis thaliana | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| all-trans-nonaprenyl diphosphate + homogentisate | Chlamydomonas reinhardtii | the enzyme is involved in biosynthesis pathway of plastoquinol-9 | diphosphate + 2-methyl-6-all-trans-nonaprenylbenzene-1,4-diol + CO2 | - |
? | |
| all-trans-nonaprenyl diphosphate + homogentisate | Arabidopsis thaliana | the enzyme is involved in biosynthesis pathway of plastoquinol-9 | diphosphate + 2-methyl-6-all-trans-nonaprenylbenzene-1,4-diol + CO2 | - |
? | |
| all-trans-nonaprenyl diphosphate + homogentisate | Chlamydomonas reinhardtii CC-1690 | the enzyme is involved in biosynthesis pathway of plastoquinol-9 | diphosphate + 2-methyl-6-all-trans-nonaprenylbenzene-1,4-diol + CO2 | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Arabidopsis thaliana | Q9SF04 | - |
- |
| Chlamydomonas reinhardtii | A1JHN0 | - |
- |
| Chlamydomonas reinhardtii CC-1690 | A1JHN0 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| all-trans-nonaprenyl diphosphate + homogentisate | the enzyme is involved in biosynthesis pathway of plastoquinol-9 | Chlamydomonas reinhardtii | diphosphate + 2-methyl-6-all-trans-nonaprenylbenzene-1,4-diol + CO2 | - |
? | |
| all-trans-nonaprenyl diphosphate + homogentisate | the enzyme is involved in biosynthesis pathway of plastoquinol-9 | Arabidopsis thaliana | diphosphate + 2-methyl-6-all-trans-nonaprenylbenzene-1,4-diol + CO2 | - |
? | |
| all-trans-nonaprenyl diphosphate + homogentisate | highest activities with solanesyl diphosphate, hardly active with phytyl diphosphat | Arabidopsis thaliana | diphosphate + 2-methyl-6-all-trans-nonaprenylbenzene-1,4-diol + CO2 | 2-methyl-6-all-trans-nonaprenylbenzene-1,4-diol i.e. 2-methyl-6-solanesylbenzene-1,4-diol | ? | |
| all-trans-nonaprenyl diphosphate + homogentisate | highest activity with solanesyl diphosphate, hardly active with phytyl diphosphat | Chlamydomonas reinhardtii | diphosphate + 2-methyl-6-all-trans-nonaprenylbenzene-1,4-diol + CO2 | 2-methyl-6-all-trans-nonaprenylbenzene-1,4-diol i.e. 2-methyl-6-solanesylbenzene-1,4-diol | ? | |
| all-trans-nonaprenyl diphosphate + homogentisate | the enzyme is involved in biosynthesis pathway of plastoquinol-9 | Chlamydomonas reinhardtii CC-1690 | diphosphate + 2-methyl-6-all-trans-nonaprenylbenzene-1,4-diol + CO2 | - |
? | |
| all-trans-nonaprenyl diphosphate + homogentisate | highest activity with solanesyl diphosphate, hardly active with phytyl diphosphat | Chlamydomonas reinhardtii CC-1690 | diphosphate + 2-methyl-6-all-trans-nonaprenylbenzene-1,4-diol + CO2 | 2-methyl-6-all-trans-nonaprenylbenzene-1,4-diol i.e. 2-methyl-6-solanesylbenzene-1,4-diol | ? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| At3g11950 | - |
Arabidopsis thaliana |
| AtHST | - |
Arabidopsis thaliana |
| CrHST | - |
Chlamydomonas reinhardtii |
| HST | - |
Chlamydomonas reinhardtii |
| PDS2 | - |
Chlamydomonas reinhardtii |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 28 | - |
assay at | Chlamydomonas reinhardtii |
| 28 | - |
assay at | Arabidopsis thaliana |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8.5 | - |
assay at | Chlamydomonas reinhardtii |
| 8.5 | - |
assay at | Arabidopsis thaliana |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | the enzyme is involved in biosynthesis pathway of plastoquinol-9 | Chlamydomonas reinhardtii |
| physiological function | the enzyme is involved in biosynthesis pathway of plastoquinol-9. Overexpression of At3g11950 in Arabidopsis thaliana, however, suggests that the solanesyltransferase can affect tocopherol biosynthesis as well | Arabidopsis thaliana |
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