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Literature summary for 2.5.1.100 extracted from

  • Li, S.M.; Unsoeld, I.A.
    Post-genome research on the biosynthesis of ergot alkaloids (2006), Planta Med., 72, 1117-1120.
    View publication on PubMed
Search for more literature for 2.5.1.100

Cloned(Commentary)

Cloned (Comment) Organism
gene fgaPT1, DNA and amino acid sequence determination and analysis, genetic organization, phylogenetic analysis Aspergillus fumigatus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
fumigaclavine A + dimethylallyl diphosphate Aspergillus fumigatus
-
 fumigaclavine C + diphosphate
-
 ?
fumigaclavine A + dimethylallyl diphosphate Aspergillus fumigatus Af293
-
 fumigaclavine C + diphosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Aspergillus fumigatus
-
 gene fgaPT1, in the gene cluster of fumigaclabvine C biosynthesis
-
Aspergillus fumigatus Af293
-
 gene fgaPT1, in the gene cluster of fumigaclabvine C biosynthesis
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
fumigaclavine A + dimethylallyl diphosphate
-
 Aspergillus fumigatus fumigaclavine C + diphosphate
-
 ?
fumigaclavine A + dimethylallyl diphosphate
-
 Aspergillus fumigatus Af293 fumigaclavine C + diphosphate
-
 ?

Synonyms

Synonyms Comment Organism
FgaPT1
-
 Aspergillus fumigatus

General Information

General Information Comment Organism
metabolism FgaPT1 catalyzes the last step of fumigaclavine C biosynthesis, i.e. the prenylation of fumigaclavine A at C-2 position of the indole nucleus, which is included in the biosynthesis of ergot alkaloids Aspergillus fumigatus