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Literature summary for 2.5.1.10 extracted from

  • Takahashi, H.; Aihara, Y.; Ogawa, Y.; Murata, Y.; Nakajima, K.I.; Iida, M.; Shirai, M.; Fujisaki, S.
    Suppression of phenotype of Escherichia coli mutant defective in farnesyl diphosphate synthase by overexpression of gene for octaprenyl diphosphate synthase (2018), Biosci. Biotechnol. Biochem., 82, 1003-1010 .
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
hexahistidine-tagged octaprenyl diphosphate synthase Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli P22939 K12 strain SF5
-
Escherichia coli K12 P22939 K12 strain SF5
-

Purification (Commentary)

Purification (Comment) Organism
hexahistidine-tagged octaprenyl diphosphate synthase Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(2E,6E)-farnesyl diphosphate + 5 isopentenyl diphosphate
-
Escherichia coli 5 diphosphate + all-trans-octaprenyl diphosphate
-
?
(2E,6E)-farnesyl diphosphate + 5 isopentenyl diphosphate
-
Escherichia coli K12 5 diphosphate + all-trans-octaprenyl diphosphate
-
?

Synonyms

Synonyms Comment Organism
IspA
-
Escherichia coli

General Information

General Information Comment Organism
malfunction slow growth of an Escherichia coli ispA null mutant lacking farnesyl diphosphate synthase. The growth rates of ispA mutant-transformants harboring a medium-copy number plasmid that carries ispA is almost the same as that of the wild-type strain Escherichia coli