BRENDA - Enzyme Database show
show all sequences of 2.4.99.B6

Escherichia coli heptosyltransferase I: investigation of protein dynamics of a GT-B structural enzyme

Czyzyk, D.J.; Sawant, S.S.; Ramirez-Mondragon, C.A.; Hingorani, M.M.; Taylor, E.A.; Biochemistry 52, 5158-5160 (2013)

Data extracted from this reference:

Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ADP-L-glycero-beta-D-manno-heptose + a 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid of the growing core region of lipopolysaccharide
Escherichia coli
-
?
-
-
?
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Escherichia coli
-
-
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ADP-L-glycero-beta-D-manno-heptose + a 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid of the growing core region of lipopolysaccharide
-
737682
Escherichia coli
?
-
-
-
?
ADP-L-glycero-beta-D-manno-heptose + O-deacylated Kdo2-lipidA
-
737682
Escherichia coli
?
-
-
-
?
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ADP-L-glycero-beta-D-manno-heptose + a 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid of the growing core region of lipopolysaccharide
Escherichia coli
-
?
-
-
?
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ADP-L-glycero-beta-D-manno-heptose + a 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid of the growing core region of lipopolysaccharide
-
737682
Escherichia coli
?
-
-
-
?
ADP-L-glycero-beta-D-manno-heptose + O-deacylated Kdo2-lipidA
-
737682
Escherichia coli
?
-
-
-
?
Other publictions for EC 2.4.99.B6
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
737682
Czyzyk
Escherichia coli heptosyltrans ...
Escherichia coli
Biochemistry
52
5158-5160
2013
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726955
Czyzyk
Lipopolysaccharide biosynthesi ...
Escherichia coli
Biochemistry
50
10570-10572
2011
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8
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1
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2
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6
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8
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8
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6
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8
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1
1
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8
8
727326
Durka
The inhibition of liposacchari ...
Escherichia coli
Chemistry
18
641-651
2011
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1
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1
1
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727135
Moreau
Discovery of new Gram-negative ...
Escherichia coli
Bioorg. Med. Chem. Lett.
18
4022-4026
2008
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1
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11
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10
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728139
Grizot
Structure of the Escherichia c ...
Escherichia coli
J. Mol. Biol.
363
383-394
2006
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1
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1
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1
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728049
Gronow
Characterization of the physio ...
Escherichia coli
J. Endotoxin Res.
7
263-270
2001
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727413
Gronow
Comparative functional charact ...
Escherichia coli
Eur. J. Biochem.
267
6602-6611
2000
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3
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727824
Kadrmas
Enzymatic synthesis of lipopol ...
Escherichia coli
J. Biol. Chem.
273
2799-2807
1998
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