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Literature summary for 2.4.99.18 extracted from

  • Glover, K.J.; Weerapana, E.; Numao, S.; Imperiali, B.
    Chemoenzymatic synthesis of glycopeptides with PglB, a bacterial oligosaccharyl transferase from Campylobacter jejuni (2005), Chem. Biol., 12, 1311-1315.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.4.99.18

Application

Application Comment Organism
medicine the development of powerful inhibitors of this enzyme would be valuable in the quest for antibiotics for Campylobacter jejuni-induced gastrointestinal disorders Campylobacter jejuni

Cloned(Commentary)

Cloned (Comment) Organism
preparation of a membrane fraction from Escherichia coli in which PglB has been overexpressed Campylobacter jejuni

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Campylobacter jejuni PglB transfers a wide variety of saccharides ?
-
 ?

Organism

Organism UniProt Comment Textmining
Campylobacter jejuni
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information PglB transfers a wide variety of saccharides Campylobacter jejuni ?
-
 ?
N-acetyl-D-galactosaminyl-alpha-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tritrans,heptacis-undecaprenol + KDFNVSKA
-
 Campylobacter jejuni tritrans,heptacis-undecaprenyl diphosphate + Lys-Asp-Phe-N4-[N-acetyl-D-galactosaminyl-alpha-(1->3)-N,N'-diacetyl-beta-D-bacillosaminyl]-Asn-Val-Ser-Lys-Ala
-
 ?

Synonyms

Synonyms Comment Organism
PglB
-
 Campylobacter jejuni