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Literature summary for 2.4.99.18 extracted from
- Oligosaccharyltransferase isoforms that contain different catalytic STT3 subunits have distinct enzymatic properties (2003), Mol. Cell, 12, 101-111.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | - |
Canis lupus familiaris | - |
- |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Canis lupus familiaris | - |
- |
- |
| Homo sapiens | - |
- |
- |
| Mus musculus | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| glycoprotein | subunits STT3-A and STT3-B are both glycosylated | Canis lupus familiaris |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| CH12.LX cell | lymphoma cell line CH12-LX | Mus musculus | - |
| pancreas | - |
Canis lupus familiaris | - |
| skin fibroblast | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Glc3Man9GlcNAc2 dolichyl diphosphate + protein L-asparagine | - |
Canis lupus familiaris | ? | - |
? |  |
| Man9GlcNAc2PP dolichyl diphosphate + protein L-asparagine | - |
Canis lupus familiaris | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| More | subunit STT3-A and SST3-B are both expressed in lymphoma cell line CH12-LX | Mus musculus |
| More | subunit STT3-A and SST3-B are both expressed in skin fibroblasts | Homo sapiens |
| More | subunit STT3-A is only recovered in the OST-III peak, while STT3-B subunit coelutes with OST-I and OST-II. Oligosaccharyltransferase isoforms that contain different catalytic STT3 subunits have distinct enzymatic properties. OST isoforms that incorporate STT3-B as a subunit are substantially more active and show a reduced ability to discriminate between donor substrates with different oligosaccharide structures | Canis lupus familiaris |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| oligosaccharyltransferase | - |
Mus musculus |
| oligosaccharyltransferase | - |
Homo sapiens |
| oligosaccharyltransferase | - |
Canis lupus familiaris |
| OST-I | - |
Canis lupus familiaris |
| OST-II | - |
Canis lupus familiaris |
| OST-III | - |
Canis lupus familiaris |
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Release 2023.1 (January 2023)
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