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Literature summary for 2.4.3.9 extracted from

  • Paccalet, T.; Coulombe, Z.; Tremblay, J.P.
    Ganglioside GM3 levels are altered in a mouse model of HIBM: GM3 as a cellular marker of the disease (2010), PLoS ONE, 5, e10055.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.4.3.9

Application

Application Comment Organism
medicine the enzyme is a marker of hereditary inclusion body myopathy Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus O88829
-
-

Source Tissue

Source Tissue Comment Organism Textmining
muscle
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-beta-D-glucosylceramide
-
 Mus musculus CMP + N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide
-
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Synonyms

Synonyms Comment Organism
beta-galactoside alpha-2,3-sialyltransferase 5
-
 Mus musculus
ST3Gal5
-
 Mus musculus

Expression

Organism Comment Expression
Mus musculus enzyme mRNA levels are significantly lower (64%) in mouse muscles of a model of hereditary inclusion body myopathy harboring the M712T mutation of UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase compared to control mice down