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Literature summary for 2.4.3.8 extracted from

  • Pohlentz, G.; Klein, D.; Schwarzmann, G.; Schmitz, D.; Sandhoff, K.
    Both GA2, GM2, and GD2 synthases and GM1b, GD1a, and GT1b synthases are single enzymes in Golgi vesicles from rat liver (1988), Proc. Natl. Acad. Sci. USA, 85, 7044-7048 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.4.3.8

Inhibitors

Inhibitors Comment Organism Structure
ganglioside GQ1b
-
 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
Golgi vesicle
-
 Rattus norvegicus
-
-

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CMP-N-acetylneuraminate + ganglioside GM3 ganglioside GM3 i.e. 1-O-[O-(N-acetyl-alpha-neuraminyl)-(2->3)-O-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranosyl]-ceramideganglioside Rattus norvegicus CMP + ganglioside GD3
-
 ?

Synonyms

Synonyms Comment Organism
GD3 synthase
-
 Rattus norvegicus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Rattus norvegicus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.35
-
 assay at Rattus norvegicus