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Literature summary for 2.4.3.6 extracted from

  • Peracaula, R.; Tabares, G.; Lopez-Ferrer, A.; Brossmer, R.; de Bolos, C.; de Llorens, R.
    Role of sialyltransferases involved in the biosynthesis of Lewis antigens in human pancreatic tumour cells (2005), Glycoconj. J., 22, 135-144 .
    View publication on PubMed
Search for more literature for 2.4.3.6

Organism

Organism UniProt Comment Textmining
Homo sapiens Q11206
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Source Tissue

Source Tissue Comment Organism Textmining
adenocarcinoma cell Capan-1 cell, Panc-1 cell, MDAPanc-3 cell, Capan-1 cell. The level of the ST3Gal III transcripts can not be associated with the degree of differentiation of the tumours from which the cell lines are derived Homo sapiens
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CAPAN-1 cell
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 Homo sapiens
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MDA-Panc-3 cell
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 Homo sapiens
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PANC-1 cell
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 Homo sapiens
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pancreas normal pancreas has around 40% less quantity of ST3Gal IV transcript compared to the positive tumour cell lines. The level of the ST3Gal III transcripts can not be associated with the degree of differentiation of the tumours from which the cell lines are derived Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CMP-N-acetyl-beta-neuraminate + beta-D-Gal-(1->4)-beta-D-GlcNAc-[protein]
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 Homo sapiens CMP + alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-[protein]
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 ?

Synonyms

Synonyms Comment Organism
ST3Gal IV
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 Homo sapiens

General Information

General Information Comment Organism
metabolism involvement in the formation of the sialyl-Lewis antigens Homo sapiens