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Literature summary for 2.4.3.5 extracted from

  • Pieringer, J.; Keech, S.; Pieringer, R.A.
    Biosynthesis in vitro of sialosylgalactosyldiacylglycerol by mouse brain microsomes (1981), J. Biol. Chem., 256, 12306-12309.
    View publication on PubMed
Search for more literature for 2.4.3.5

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.13
-
 galactosyldiacylglycerol
-
 Mus musculus
0.78
-
 CMP-acetylneuraminate
-
 Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Mus musculus 16020
-
microsome
-
 Mus musculus
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
CMP-N-acetylneuraminate + 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol Mus musculus i.e. galactosyldiacylglycerol, transfers N-acetylneuraminic acid to position C-3 of the galactosyl residue CMP + 1,2-diacyl-3-[3-(alpha-D-N-acetylneuraminyl)-beta-D-galactosyl]-sn-glycerol i.e. sialosylgalactosyldiacylglycerol ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
 Swiss-Webster albino
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CMP-N-acetylneuraminate + 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol i.e. galactosyldiacylglycerol, transfers N-acetylneuraminic acid to position C-3 of the galactosyl residue Mus musculus CMP + 1,2-diacyl-3-[3-(alpha-D-N-acetylneuraminyl)-beta-D-galactosyl]-sn-glycerol i.e. sialosylgalactosyldiacylglycerol ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Mus musculus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.2
-
-
 Mus musculus