Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q11201 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
MDA-MB-231 cell | - |
Homo sapiens | - |
T-47D cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
CMP-N-acetyl-beta-neuraminate + beta-D-Gal-(1->3)-beta-D-GalNAc | - |
Homo sapiens | CMP + alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ST3Gal-I | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | induction of COX-2 in the MDAMB-231 breast cancer cell line results in the increased expression of ST3Gal-I, leading to increased sialylation of the substrate of ST3Gal-I | up |
Homo sapiens | PGE2, one of the final products of the cyclooxygenase-2 (COX-2) pathway, can induce the mRNA expression of the sialyltransferase ST3Gal-I, resulting in increased sialyltransferase activity | up |