Literature summary for 2.4.3.2 extracted from

Perez-Garay, M.; Arteta, B.; Llop, E.; Cobler, L.; Pages, L.; Ortiz, R.; Ferri, M.J.; de Bolos, C.; Figueras, J.; de Llorens, R.; Vidal-Vanaclocha, F.; Peracaula, R.
alpha2,3-Sialyltransferase ST3Gal IV promotes migration and metastasis in pancreatic adenocarcinoma cells and tends to be highly expressed in pancreatic adenocarcinoma tissues (2013), Int. J. Biochem. Cell Biol., 34, 1748-1757 .

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Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q11206	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
MDA-Panc-28 cell	ST3Gal IV overexpressing pancreatic adenocarcinoma cell lines	Homo sapiens	-
pancreatic adenocarcinoma cell	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
CMP-N-acetyl-beta-neuraminate + ganglioside GM1a	-	Homo sapiens	CMP + ganglioside GD1a	-	?

Synonyms

Synonyms	Comment	Organism
ST3Gal IV	-	Homo sapiens

Expression

Organism	Comment	Expression
Homo sapiens	highly expressed in most pancreatic adenocarcinoma tissues	up

General Information

General Information	Comment	Organism
physiological function	the enzyme is involved in pancreatic tumor progression processes	Homo sapiens

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Release 2023.1 (January 2023)