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Literature summary for 2.4.3.2 extracted from

  • Iber, H.; van Echten, G.; Sandhoff, K.
    Substrate specificity of alpha 2->3-sialyltransferases in ganglioside biosynthesis of rat liver Golgi (1991), Eur. J. Biochem., 195, 115-120.
    View publication on PubMed
Search for more literature for 2.4.3.2

Activating Compound

Activating Compound Comment Organism Structure
Triton CF-54 activation Rattus norvegicus
Triton X-100 slight activation Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
ganglioside GM3 in the presence of Triton CF-54 Rattus norvegicus
lactosylceramide inhibits reaction with GM1a Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
Golgi apparatus
-
 Rattus norvegicus 5794
-

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CMP-N-acetyl-beta-neuraminate + ganglioside GA1
-
 Rattus norvegicus CMP + ganglioside GM1b
-
 ?
CMP-N-acetyl-beta-neuraminate + ganglioside GD1b
-
 Rattus norvegicus CMP + ganglioside GT1b
-
 ?
CMP-N-acetyl-beta-neuraminate + ganglioside GM1a
-
 Rattus norvegicus CMP + ganglioside GD1a i.e. ganglioside GD1a ?

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
56
-
 t1/2: 60 s Rattus norvegicus

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
additional information
-
 additional information
-
 Rattus norvegicus