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Literature summary for 2.4.3.10 extracted from

  • Paulson, J.; Weinstein, J.; de Souza-e-Silva, U.
    Biosynthesis of a disialylated sequence in N-linked oligosaccharides Identification of an N-acetylglucosaminide (alpha2->6)-sialyltransferase in Golgi apparatus from rat liver (1984), Eur. J. Biochem., 140, 523-530 .
    View publication on PubMed
Search for more literature for 2.4.3.10

Localization

Localization Comment Organism GeneOntology No. Textmining
Golgi apparatus
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 Rattus norvegicus 5794
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
CMP-N-acetyl-beta-neuraminate + N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-R Rattus norvegicus the enzyme has a marked preference for the sequence NeuAcalpha(2->3)-Galbeta(1->3)GlcNAc as an acceptor substrate CMP + N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminyl-(2->6)]-N-acetyl-beta-D-glucosaminyl-R
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 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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-
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Source Tissue

Source Tissue Comment Organism Textmining
liver
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 Rattus norvegicus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CMP-N-acetyl-beta-neuraminate + N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-R the enzyme has a marked preference for the sequence NeuAcalpha(2->3)-Galbeta(1->3)GlcNAc as an acceptor substrate Rattus norvegicus CMP + N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminyl-(2->6)]-N-acetyl-beta-D-glucosaminyl-R
-
 ?
CMP-N-acetyl-beta-neuraminate + N-acetylneuramin-lacto-N-tetraose a
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 Rattus norvegicus CMP + disialyllacto-N-tetraose
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 ?

Synonyms

Synonyms Comment Organism
CMP-N-acetylneuraminate : N-acetylglucosaminide (alpha2->6)-sialyltransferase
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 Rattus norvegicus
N-acetylglucosaminide (alpha2->6)-sialyltransferase
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 Rattus norvegicus