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Literature summary for 2.4.3.1 extracted from

  • Chen, X.; Wang, L.; Yu, X.; Wang, S.; Zhang, J.
    Caveolin-1 facilitates cell migration by upregulating nuclear receptor 4A2/retinoid X receptor alpha-mediated beta-galactoside alpha2,6-sialyltransferase I expression in human hepatocarcinoma cells (2021), Int. J. Biochem. Cell Biol., 137, 106027 .
    View publication on PubMed
Search for more literature for 2.4.3.1

Application

Application Comment Organism
medicine increased enzyme expression in hepatocellular carcinoma tissues correlates with poor prognosis Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
nucleus
-
 Homo sapiens 5634
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
CMP-N-acetyl-beta-neuraminate + beta-D-galactosyl-R Homo sapiens
-
 CMP + N-acetyl-alpha-neuraminyl-(2->6)-beta-D-galactosyl-R
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
Hep-G2 cell
-
 Homo sapiens
-
hepatoma cell
-
 Homo sapiens
-
Huh-7 cell
-
 Homo sapiens
-
MHCC97-H cell
-
 Homo sapiens
-
MHCC97-L cell
-
 Homo sapiens
-
SMMC-7721 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CMP-N-acetyl-beta-neuraminate + beta-D-galactosyl-R
-
 Homo sapiens CMP + N-acetyl-alpha-neuraminyl-(2->6)-beta-D-galactosyl-R
-
 ?

Subunits

Subunits Comment Organism
? x * 47000, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
beta-galactoside alpha2,6-sialyltransferase I
-
 Homo sapiens
ST6Gal-I
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens the expression level of the enzyme is increased in hepatocellular carcinoma tissues. Caveolin-1 upregulates the enyzme expression up