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Literature summary for 2.4.3.1 extracted from

  • Zhou, L.; Zhang, S.; Zou, X.; Lu, J.; Yang, X.; Xu, Z.; Shan, A.; Jia, W.; Liu, F.; Yan, X.; Su, H.; Liang, T.; Zheng, M.; Zhang, Y.; Feng, B.
    The beta-galactoside alpha2,6-sialyltranferase 1 (ST6GAL1) inhibits the colorectal cancer metastasis by stabilizing intercellular adhesion molecule-1 via sialylation (2019), Cancer Manag. Res., 11, 6185-6199 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.4.3.1

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
colorectal cancer cell
-
 Homo sapiens
-
SW-480 cell
-
 Homo sapiens
-
SW-620 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CMP-N-acetyl-beta-neuraminate + intercellular adhesion molecule-1 the enzyme can increase the stability of intercellular adhesion molecule-1 through sialylation Homo sapiens CMP + ?
-
 ?

Subunits

Subunits Comment Organism
? x * 56000, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
beta-galactoside alpha2,6-sialyltranferase 1
-
 Homo sapiens
ST6Gal1
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function the enzyme inhibits the colorectal cancer metastasis by stabilizing intercellular adhesion molecule-1 via sialylation Homo sapiens