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Literature summary for 2.4.3.1 extracted from

  • Schur, M.J.; Lameignere, E.; Strynadka, N.C.; Wakarchuk, W.W.
    Characterization of alpha2,3- and alpha2,6-sialyltransferases from Helicobacter acinonychis (2012), Glycobiology, 22, 997-1006.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.4.3.1

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli strain AD202 Helicobacter acinonychis

Inhibitors

Inhibitors Comment Organism Structure
Mn2+ about 75% activity in the presence of 10 mM Mn2+ Helicobacter acinonychis
additional information not inhibited by EDTA Helicobacter acinonychis

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ about 120% activity in the presence of 10 mM Mg2+ Helicobacter acinonychis

Organism

Organism UniProt Comment Textmining
Helicobacter acinonychis Q17WF8
-
-
Helicobacter acinonychis ATCC 51104 Q17WF8
-
-

Purification (Commentary)

Purification (Comment) Organism
amylose column chromatography Helicobacter acinonychis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosamine highest activity Helicobacter acinonychis CMP + alpha-N-acetylneuraminyl-2,6-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosamine
-
 ?
CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosamine highest activity Helicobacter acinonychis ATCC 51104 CMP + alpha-N-acetylneuraminyl-2,6-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosamine
-
 ?
additional information no activity with Gal-beta1,3-GlcNAc, T-antigen Gal-beta1,3-GalNAc-alpha, and NeuAc-alpha2,3-Gal-beta1,4-Glc Helicobacter acinonychis ?
-
 ?
additional information no activity with Gal-beta1,3-GlcNAc, T-antigen Gal-beta1,3-GalNAc-alpha, and NeuAc-alpha2,3-Gal-beta1,4-Glc Helicobacter acinonychis ATCC 51104 ?
-
 ?

Synonyms

Synonyms Comment Organism
alpha2,6-sialyltransferase
-
 Helicobacter acinonychis
HAC1268
-
 Helicobacter acinonychis

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6
-
-
 Helicobacter acinonychis