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Literature summary for 2.4.3.1 extracted from

  • Ding, J.X.; Xu, L.X.; Zhu, L.; Lv, J.C.; Zhao, M.H.; Zhang, H.; Wang, H.Y.
    Activity of alpha2,6-sialyltransferase and its gene expression in peripheral B lymphocytes in patients with IgA nephropathy (2009), Scand. J. Immunol., 69, 174-180.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
-

Source Tissue

Source Tissue Comment Organism Textmining
B-lymphocyte
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Homo sapiens
-

Synonyms

Synonyms Comment Organism
alpha2,6-sialyltransferase
-
Homo sapiens
alpha2,6-ST
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Homo sapiens
ST6GALNAC2
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Homo sapiens

Expression

Organism Comment Expression
Homo sapiens expression of ST6GALNAC2 in B peripheral lymphocytes is significantly lower in patients with IgA nephropathy than that in normal controls down
Homo sapiens alpha2,6-ST activity in B lymphocytes is correlated positively with the level of alpha2,6-sialic acid in serum IgA1 in patients and controls up

General Information

General Information Comment Organism
physiological function reduced sialylation of serum IgA1 may result from decreased expression of ST6GALNAC2 Homo sapiens