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Literature summary for 2.4.3.1 extracted from

  • Kajihara, Y.; Kamitani, T.; Sato, R.; Kamei, N.; Miyazaki, T.; Okamoto, R.; Sakakibara, T.; Tsuji, T.; Yamamoto, T.
    Synthesis of CMP-9-modified-sialic acids as donor substrate analogues for mammalian and bacterial sialyltransferases (2007), Carbohydr. Res., 342, 1680-1688.
    View publication on PubMed
Search for more literature for 2.4.3.1

Application

Application Comment Organism
synthesis the Photobacterium sialyltransferase can be used in the synthesis of sialoside analogues having a large substituent at the 9-position of Neu5Ac Photobacterium sp.

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.05
-
 CMP-9''-phenylacetamido-Neu5Ac pH 5.0, 37°C Rattus norvegicus
0.051
-
 CMP-9''-benzamido-Neu5Ac pH 5.0, 37°C Rattus norvegicus
0.098
-
 CMP-9''-phenylhexanamido-Neu5Ac pH 5.0, 37°C Rattus norvegicus
0.11
-
 CMP-9''-benzamido-Neu5Ac pH 5.0, 37°C Photobacterium sp.
0.11
-
 CMP-9''-phenylpropionamido-Neu5Ac pH 5.0, 37°C Photobacterium sp.
0.12
-
 cytidine-5'-monophospho-sialic acid pH 5.0, 37°C Rattus norvegicus
0.14
-
 cytidine-5'-monophospho-sialic acid pH 5.0, 37°C Photobacterium sp.
0.165
-
 CMP-9''-phenylpropionamido-Neu5Ac pH 5.0, 37°C Rattus norvegicus
0.34
-
 CMP-9''-phenylacetamido-Neu5Ac pH 5.0, 37°C Photobacterium sp.
0.53
-
 CMP-9''-phenylhexanamido-Neu5Ac pH 5.0, 37°C Photobacterium sp.
1.8
-
 lactose pH 5.0, 37°C, cosubstrate: CMP-9''-benzamido-Neu5Ac Photobacterium sp.
2
-
 N-acetyllactosamine pH 5.0, 37°C, cosubstrate: CMP-9''-phenylacetamido-Neu5Ac Rattus norvegicus
2.5
-
 lactose pH 5.0, 37°C, cosubstrate: CMP-9''-phenylacetamido-Neu5Ac Photobacterium sp.
2.5
-
 lactose pH 5.0, 37°C, cosubstrate: CMP-phenylhexanamido-Neu5Ac Photobacterium sp.
2.6
-
 lactose pH 5.0, 37°C, cosubstrate: CMP-phenylpropionamido-Neu5Ac Photobacterium sp.
3.6
-
 lactose pH 5.0, 37°C, cosubstrate: cytidine-5'-monophospho-sialic acid Photobacterium sp.
4.3
-
 N-acetyllactosamine pH 5.0, 37°C, cosubstrate: cytidine-5'-monophospho-sialic acid Rattus norvegicus
5.2
-
 N-acetyllactosamine pH 5.0, 37°C, cosubstrate: CMP-9''-phenylhexanamido-Neu5Ac Rattus norvegicus
6.8
-
 N-acetyllactosamine pH 5.0, 37°C, cosubstrate: CMP-9''-benzamido-Neu5Ac Rattus norvegicus
10
-
 N-acetyllactosamine pH 5.0, 37°C, cosubstrate: CMP-9''-phenylpropionamido-Neu5Ac Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Photobacterium sp.
-
-
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CMP-9''-benzamido-Neu5Ac + lactose
-
 Photobacterium sp. ?
-
 ?
CMP-9''-benzamido-Neu5Ac + N-acetyllactosamine
-
 Rattus norvegicus ?
-
 ?
CMP-9''-phenylacetamido-Neu5Ac + lactose
-
 Photobacterium sp. ?
-
 ?
CMP-9''-phenylacetamido-Neu5Ac + N-acetyllactosamine
-
 Rattus norvegicus ?
-
 ?
CMP-9''-phenylhexanamido-Neu5Ac + lactose
-
 Photobacterium sp. ?
-
 ?
CMP-9''-phenylhexanamido-Neu5Ac + N-acetyllactosamine
-
 Rattus norvegicus ?
-
 ?
CMP-9''-phenylpropionamido-Neu5Ac + lactose
-
 Photobacterium sp. ?
-
 ?
CMP-9''-phenylpropionamido-Neu5Ac + N-acetyllactosamine
-
 Rattus norvegicus ?
-
 ?
cytidine-5'-monophospho-sialic acid + lactose
-
 Photobacterium sp. ?
-
 ?
cytidine-5'-monophospho-sialic acid + N-acetyllactosamine
-
 Rattus norvegicus ?
-
 ?

Synonyms

Synonyms Comment Organism
6STase
-
 Rattus norvegicus
6STase
-
 Photobacterium sp.
alpha-(2->6)-sialyltransferase
-
 Rattus norvegicus
alpha-(2->6)-sialyltransferase
-
 Photobacterium sp.