Literature summary for 2.4.3.1 extracted from

Choi, H.J.; Park, Y.G.; Kim, C.H.
Lactosylceramide alpha2,3-sialyltransferase is induced via a PKC/ERK/CREB-dependent pathway in K562 human leukemia cells (2007), Mol. Cell, 23, 138-144.

Search for more literature for 2.4.3.1

Activating Compound

Activating Compound	Comment	Organism	Structure
additional information	the enzyme is induced by phorbol 12-myristate 13-acetate via a PKC/ERK/CREB-dependent pathway in K562 human leukemia cells, the induction is inhibited by Gö6976, a specific inhibitor of PKC, and U0126, an inhibitor of the extracellular signal-regulated kinase, but not by wortmannin, overview	Homo sapiens

Cloned(Commentary)

Cloned (Comment)	Organism
expression analysis	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
K-562 cell	a leukemia cell line, the enzyme is expressed during the induction of megakaryocytic differentiation	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
CMP-NeuAc:lactosylceramide alpha2,3-sialyltransferase	-	Homo sapiens
GM3 synthase	-	Homo sapiens
lactosylceramide alpha2,3-sialyltransferase	-	Homo sapiens

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Release 2023.1 (January 2023)