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Literature summary for 2.4.3.1 extracted from
- Multiple signals are required for alpha2,6-sialyltransferase (ST6Gal I) oligomerization and Golgi localization (2005), J. Biol. Chem., 280, 5423-5429.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in COS cells | Rattus norvegicus |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| Golgi apparatus | the STtyr isoform is transiently localized in the Golgi and is ultimately cleaved and secreted, whereas the STcys isoform is stably localized in the Golgi and is not cleaved and secreted. Cytosolic tail and transmembrane region of the ST6Gal I both play roles in Golgi localization | Rattus norvegicus | 5794 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| oligomer | STcys oligomerization is a secondary event resulting from its concentration in the Golgi via mechanisms independently mediated by its cytosolic tail and transmembrane region | Rattus norvegicus |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| alpha2,6-sialyltransferase ST6Gal I | - |
Rattus norvegicus |
| ST6Gal I | - |
Rattus norvegicus |
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