Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.4.3.1 extracted from

  • Galan, M.C.; Venot, A.P.; Boons, G.J.
    Glycosyltransferase activity can be modulated by small conformational changes of acceptor substrates (2003), Biochemistry, 42, 8522-8529.
    View publication on PubMed
Search for more literature for 2.4.3.1

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1
-
 N-((1R,3R,5R,6R,7S,8R,14R,16R,17R,18R)-6,7,18-trihydroxy-5-hydroxymethyl-16-methoxy-11-oxo-2,4,9,15-tetraoxa-12-aza-tricyclo[12.3.1.03,8]octadec-17-yl)-acetamide pH 6.5, 37°C Rattus norvegicus
1.1
-
 N-((1R,3R,5R,6R,7S,8R,14R,16R,17R,18S)-6,7,18-Trihydroxy-5-hydroxymethyl-16-methoxy-2,4,9,12,15-pentaoxa-tricyclo[12.3.1.03,8]octadec-17-yl)-acetamide pH 6.5, 37°C Rattus norvegicus
1.7
-
 Galbeta(1-3)GlcNAcbeta-O-Me pH 6.5, 37°C Rattus norvegicus
3.3
-
 Formic acid (2R,3R,4S,5R,6R)-2-((2R,3R,4R,5R,6R)-3-acetylamino-5-hydroxy-2-methoxy-6-methylaminomethyl-tetrahydro-pyran-4-yloxy)-4,5-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-3-yl ester pH 6.5, 37°C Rattus norvegicus
11.2
-
 (Gal-3-O-Me)beta(1-3)(GlcNAc-6-O-Me)beta-O-Me pH 6.5, 37°C Rattus norvegicus
11.6
-
 N-((1R,3R,5R,6R,7S,8R,13R,15R,16R,17S)-6,7,17-Trihydroxy-5-hydroxymethyl-15-methoxy-2,4,9,11,14-pentaoxa-tricyclo[11.3.1.03,8]heptadec-16-yl)-acetamide pH 6.5, 37°C Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CMP-N-acetylneuraminate + (Gal-3-O-Me)beta(1-3)(GlcNAc-6-O-Me)beta-O-Me 50% of the activity with Galbeta(1-3)GlcNAcbeta-O-Me Rattus norvegicus CMP + ?
-
 ?
CMP-N-acetylneuraminate + formic acid (2R,3R,4S,5R,6R)-2-((2R,3R,4R,5R,6R)-3-acetylamino-5-hydroxy-2-methoxy-6-methylaminomethyl-tetrahydro-pyran-4-yloxy)-4,5-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-3-yl ester as active as Galbeta(1-3)GlcNAcbeta-O-Me Rattus norvegicus CMP + ?
-
 ?
CMP-N-acetylneuraminate + Galbeta(1-3)GlcNAcbeta-O-Me
-
 Rattus norvegicus CMP + NeuAcalpha(2-6)Galbeta(1-3)GlcNAcbeta-O-Me
-
 ?
CMP-N-acetylneuraminate + N-((1R,3R,5R,6R,7S,8R,13R,15R,16R,17S)-6,7,17-trihydroxy-5-hydroxymethyl-15-methoxy-2,4,9,11,14-pentaoxa-tricyclo[11.3.1.03,8]heptadec-16-yl)-acetamide as active as Galbeta(1-3)GlcNAcbeta-O-Me Rattus norvegicus CMP + ?
-
 ?
CMP-N-acetylneuraminate + N-((1R,3R,5R,6R,7S,8R,14R,16R,17R,18R)-6,7,18-trihydroxy-5-hydroxymethyl-16-methoxy-11-oxo-2,4,9,15-tetraoxa-12-aza-tricyclo[12.3.1.03,8]octadec-17-yl)-acetamide 110% of the activity with Galbeta(1-3)GlcNAcbeta-O-Me Rattus norvegicus CMP + ?
-
 ?
CMP-N-acetylneuraminate + N-((1R,3R,5R,6R,7S,8R,14R,16R,17R,18S)-6,7,18-trihydroxy-5-hydroxymethyl-16-methoxy-2,4,9,12,15-pentaoxa-tricyclo[12.3.1.03,8]octadec-17-yl)-acetamide 130% of the activity with Galbeta(1-3)GlcNAcbeta-O-Me Rattus norvegicus CMP + ?
-
 ?

Synonyms

Synonyms Comment Organism
R-2,6-sialyltransferase
-
 Rattus norvegicus