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Literature summary for 2.4.2.8 extracted from
- Purification and characterization of guanine phosphoribosyltransferase from Giardia lamblia (1986), J. Biol. Chem., 261, 8528-8533.
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 29000 | - |
2 * 29000, SDS-PAGE | Giardia intestinalis |
| 58000 | 63000 | gel filtration, isokinetic sucrose density gradient centrifugation | Giardia intestinalis |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Giardia intestinalis | - |
3 charge variant forms | - |
| Giardia intestinalis Portland | - |
3 charge variant forms | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Giardia intestinalis |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| trophozoite | - |
Giardia intestinalis | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Giardia intestinalis |
Storage Stability
| Storage Stability | Organism |
|---|---|
| -80°C | Giardia intestinalis |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| guanine + 5-phospho-alpha-D-ribose 1-diphosphate | - |
Giardia intestinalis | GMP + diphosphate | - |
? |  |
| guanine + 5-phospho-alpha-D-ribose 1-diphosphate | - |
Giardia intestinalis Portland | GMP + diphosphate | - |
? | |
| hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate | - |
Giardia intestinalis | IMP + diphosphate | - |
? | |
| hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate | - |
Giardia intestinalis Portland | IMP + diphosphate | - |
? | |
| xanthine + 5-phospho-alpha-D-ribose 1-diphosphate | - |
Giardia intestinalis | XMP + diphosphate | - |
? | |
| xanthine + 5-phospho-alpha-D-ribose 1-diphosphate | - |
Giardia intestinalis Portland | XMP + diphosphate | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | 2 * 29000, SDS-PAGE | Giardia intestinalis |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| additional information | - |
3 charge variant forms: pIs of 6.75, 5.3, 5.2 | Giardia intestinalis |
| 7 | 9 | broad maximum | Giardia intestinalis |
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Release 2023.1 (January 2023)
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