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Literature summary for 2.4.2.7 extracted from

  • Holden, J.A.; Meredith, G.S.; Kelley, W.N.
    Human adenine phosphoribosyltransferase. Affinity purification, subunit structure, amino acid composition, and peptide mapping (1979), J. Biol. Chem., 254, 6951-6955.
    View publication on PubMed
Search for more literature for 2.4.2.7

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.006
-
 5-phospho-alpha-D-ribose 1-diphosphate
-
 Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
38200
-
 sedimentation equilibrium centrifugation Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
erythrocyte
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
21.8
-
 purified enzyme Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
adenine + 5-phospho-alpha-D-ribose 1-diphosphate
-
 Homo sapiens AMP + diphosphate
-
 ?

Subunits

Subunits Comment Organism
dimer 2 * 17000-20000, SDS-PAGE, gel filtration in guanidine hydrochloride, peptide mapping data suggest that the subunits are quite similar if not identical Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
 assay at Homo sapiens